产品简介
英文名称
Anti-CYBB Polyclonal Antibody
宿主
Rabbit
别名
AMCBX2;CGD;GP91-1;GP91-PHOX;GP91PHOX;IMD34;NOX2;p91-PHOX;CYBB
稀释比例
WB 1:1000-3000.
蛋白分子量
65kDa
Gene ID
1536
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG
免疫原
A synthetic peptide of human CYBB
亚细胞定位
Cell membrane
Swiss Prot
P04839
背景资料
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Public Immunogen Range
490-540/570aa
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
WB
规格
50ul 100ul
 
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with CYBB antibody diluted at 1:2000;Lane:Mouse brain,Rat brain