重组甲型流感H1N1(A/California/04/2009)NA, His Tag蛋白-蛋白质/抗原/多肽-试剂-生物在线

重组甲型流感H1N1(A/California/04/2009)NA, His Tag蛋白

商家询价

产品名称：重组甲型流感H1N1(A/California/04/2009)NA, His Tag蛋白

英文名称： NA

产品编号： 11058-V07H

产品价格： 0

产品产地：北京

品牌商标：义翘神州(SinoBiological)

更新时间： null

使用范围： null

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产品详情

官方网址：http://www.sinobiological.cn/H1N1-Neuraminidase-Protein-g-1727.html

Influenza A H1N1 ( A/California/04/2009 ) Neuraminidase Protein

H1N1 NA Protein Price Inquiry ( Available Sizes )

500μg: 询价;
≥1mg 大包装: 询价

H1N1 NA蛋白产品信息

Synonym:	NA
表达方式:	A DNA sequence encoding the mature form of Influenza A virus ( A/California/04/2009 (H1N1) ) Neuraminidase ( ACP41107.1 )（ His 36 - Lys 469 ）was fused with a polyhistidine tag at the N-terminus
种属:	Influenza A H1N1
表达宿主:	Human Cells

H1N1 NA Protein QC Testing

纯度:	> 73 % as determined by SDS-PAGE	SDS-PAGE: H1N1 NA protein
生物活性:	N / A
	Active H1N1 NA ( Catalog # 11058-VNAHC )
内毒素:	< 1.0 EU per μg of the protein as determined by the LAL method.
稳定性:	Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:	His
分子量:	The recombinant influenza H1N1 virus neuraminidase ( A/California/04/2009 (H1N1) ) comprises 450 amino acids with the predicted molecular mass of 50 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 65-75 kDa in SDS-PAGE under reducing conditions
缓冲液:	Lyophilized from sterile PBS, pH 7.4

H1N1 NA Protein Usage Guide

储存方法:	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

H1N1 NA Protein Related Products & Topics

蛋白:

Products	Source (Click for detailed Info.)	Molecule	Description	Cat No
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	Fc Tag	11058-V01H
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	His Tag	11058-V07H
Protein	Influenza Neuraminidase (NA) H1N1	NA	-	11058-VNAHC

抗体:

Products	Antigen Source (Click for detailed Info.)	Antigen Molecule	Application	Cat No
MAb	Influenza Antibody to H1N1, Mouse Anti H1N1 MAb	NA	WB, ELISA	11058-MM04

Related Influenza Virus Research Tools

H1N1 NA蛋白背景综述

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. NA, also called sialidases, specifically catalyze the hydrolysis removal of terminal sialic acid residues from viral and cellular glycoconjugates. It is known that HA binds to the sialic acid-containing receptors on the surface of host cells during initial infection, and at the end of an infectious cycle, NA cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. NA is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell. NA is a single-pass type II membrane protein which exists as a homotetramer, and the transmembrane domain is involved in lipid raft association during intracellular transport. NA is suggested to play a role in the determination of host range restriction on replication and virulence. Nine subtypes of NA have been identified, and subtypes N1 and N2 have been positively linked to epidemics in man.

参考文献

Barman, S. et al., 2000, J. Virol. 74: 6538-6545.
Colman, PM. et al., 1983, Nature. 303: 41-44.
Suzuki, T. et al., 2005, J. Virol. 79: 11705-11715.
von, Itzstein, M. 2007, Nat. Rev. Drug. Discov. 6: 967-974.

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