Anti-RELB Polyclonal Antibody
产品名称: Anti-RELB Polyclonal Antibody
英文名称: Anti-RELB Polyclonal Antibody
产品编号: K001693P
产品价格: null
产品产地: 北京
品牌商标: solarbio
更新时间: 2025-02-05T13:46:23
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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Anti-RELB Polyclonal Antibody
品牌:solarbio | 货号:K001693P
英文名称 | Anti-RELB Polyclonal Antibody |
---|---|
别名 | I-REL;IREL;REL-B |
应用 | WB |
稀释比例 | WB 1:500-2000. |
交叉反应 | Human Mouse |
蛋白分子量 | 62kDa |
Gene ID | 5971 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human RELB |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human RELB |
Subcellular Locations | Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center |
Swiss Prot | Q01201 |
克隆类型 | Polyclonal Antibody |
背景资料 | RelB, also known as I-Rel, is a member of the Rel transcription factor family which also include; RelA-p65, c-Rel, NF-kB1 p100/52 and NF-kB2 p105/50. Unlike other Rel-related protein, RelB does not bind to DNA or to inhibitor IkB, but is instead sequestered in the cytoplasm by precursor p100. Once p100 is processed, the p52/RelB complex translocates into the nucleus. RelB is also the transcription factor that has been associated most directly with dendritic cells (DCs) differentiation and function. It is upregulated and translocated into the nuclei of DC in response to various stimuli. RelB is also essential for generating a specific DC subset (CD11c +/CD11b +/CD8 -/Dec205 -) from hematopoietic stem cells. |